Protein Modification Reagents
Medchemexpress LLC HyNic-PEG2-DBCO | 2741281-12-7 | N/A | ≥95.0% | C34H38N6O5 | 10MG
HyNic-PEG2-DBCO is a bifunctional PEG-based bioconjugation linker containing a hydrazinonicotinic acid (HyNic) moiety and a dibenzocyclooctyne (DBCO) group. It enables hydrazone formation with aldehyde- or ketone-containing partners and strain-promoted azide-alkyne cycloaddition for copper-free click chemistry, making it suitable for site-selective labeling, antibody conjugation, and PROTAC linker design.
- Enables copper-free click chemistry via DBCO for rapid conjugation
- Supports hydrazone coupling through HyNic to aldehydes and ketones
- PEG2 spacer improves solubility and provides flexible linkage
- Typically supplied with ≥95.0% purity for research use
- Small research-scale packaging suitable for analytical and synthetic workflows
Medchemexpress LLC Ald-Ph-amido-C2-PEG3-azide | 1807540-88-0 | MFCD28155209 | 98.9% | 350.37 g/mol | C16H22N4O5 | 5 MG
Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker and click chemistry reagent bearing an azide functional group. It enables bioconjugation and PROTAC assembly via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC), and provides a soluble, flexible PEG spacer for linker construction.
- Contains an azide functional group for click chemistry.
- Compatible with CuAAC and SPAAC conjugation methods.
- PEG3 spacer improves solubility and linker flexibility.
- High purity suitable for research applications (>98%).
- Available in small milligram pack sizes for discovery work.
- Molecular weight 350.37 g/mol; formula C16H22N4O5.
![Carbosynth LLC. Cyclo[Arg-Ala-Asp-D-Tyr-Lys(PEG)], 25mg, MF= C34H54N10O11](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501952425.jpg-250.jpg)
Carbosynth LLC. Cyclo[Arg-Ala-Asp-D-Tyr-Lys(PEG)], 25mg, MF= C34H54N10O11
Application: Control peptide for RGD-3000-PI, salt: Trifluoroacetate Salt, one letter code: c[RADyK(PEG)], MW: 778.87
Medchemexpress LLC HY-22335 100mg Medchemexpress, Amino-PEG4-C2-amine CAS:68960-97-4 Purity:>98%
Medchemexpress, HY-22335 100mg Amino-PEG4-C2-amine CAS:68960-97-4 Amino-PEG4-C2-amine is a PEG-based (4 units) PROTAC linker can be used in the synthesis of PROTACs. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 17-(Bromoacetamido-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester | Broadpharm |930.069 | C44H85BrN2O13 | 98.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CBr | 250mg | 550804667
17-(Bromoacetamido-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester | Broadpharm |930.069 | C44H85BrN2O13 | 98.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CBr | 250mg | 550804667
STA PHARMACEUTICAL US LLC Fmoc-amino-PEG3-CH2COOH | 100 g | CAS 139338-72-0 | MDL MFCD13182400
Fmoc-amino-PEG3-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 100 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 139338-72-0
- MDL: MFCD13182400
- InChIKey: XNOJSAOJCBOZTA-UHFFFAOYSA-N
- Molecular Weight: 429.469
- Molecular Formula: C23H27NO7
- Purity: ≥95%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid
- SMILES: O=C(COCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Medchemexpress LLC Maleimide-PEG2 N-hydroxysuccinimide ester | 329364-72-9 | MFCD11041137 | 95.0% | 340.29 g/mol | C14H16N2O8 | 5 MG
Mal-PEG2-NHS is a PEG-based bifunctional linker combining a maleimide reactive group with an N-hydroxysuccinimide (NHS) ester. It enables selective conjugation between thiol and amine functional groups and is commonly used in PROTAC synthesis, bioconjugation, and antibody-drug conjugate linker construction. Supplied as a research-grade reagent for laboratory-scale synthesis and conjugation workflows.
- Enables selective thiol-to-amine conjugation via maleimide and NHS chemistries.
- Two-unit PEG spacer improves water solubility and reduces steric hindrance.
- Suitable for PROTAC synthesis, bioconjugation, and ADC linker design.
- Provided as a small-scale research reagent compatible with common solvents and buffers.
- Characterized by analytical methods and typically supplied with a certificate of analysis.
Medchemexpress LLC Pomalidomide-PEG6-C2-COOH | 2225148-49-0 | MFCD32173791 | >98.0% | C28H39N3O12 | 10MG
Pomalidomide-PEG6-C2-COOH is a cereblon E3 ligase ligand-linker conjugate that combines a pomalidomide-derived cereblon binder with a six-unit polyethylene glycol spacer terminating in a carboxylic acid. Supplied as a high-purity building block, it is intended for use in the synthesis of PROTACs and other targeted protein degradation molecules, enabling modular attachment to warheads or additional linker chemistry.
- Cereblon-binding pomalidomide core for E3 ligase recruitment.
- PEG6 spacer provides a flexible, water-compatible linker.
- Terminal carboxylic acid enables amide coupling and conjugation.
- High chemical purity suitable for medicinal chemistry research.
- Available in multiple small-scale package sizes for screening and optimisation.
- Stable under recommended storage conditions for reliable handling.
Medchemexpress LLC m-PEG-DMG | 1019000-64-6 | ≥98.0% | 2000 Da (average) | (C2H4O)nC36H73NO5 | 5 MG
m-PEG-DMG (MW 2000) is a methoxy-terminated polyethylene glycol lipid with a dimyristoyl glycerol anchor and an average molecular weight of 2,000 Da. It is intended for incorporation into liposomes and lipid nanoparticles to provide a PEG corona that enhances stability and circulation time in drug delivery research.
- Enhances colloidal stability and circulation time
- Reduces protein adsorption and opsonization
- Facilitates PEGylation of liposome and nanoparticle surfaces
- Supplied in lab-scale quantities suitable for formulation studies
- High purity for reproducible formulation performance
Medchemexpress LLC Tamra-peg4-acid | 1909223-02-4 | 95.3% | C36H43N3O10 | 25 MG
TAMRA-PEG4-acid is a dye derivative of TAMRA containing 3 PEG units. It is for research use only and not sold to patients.
- Dye derivative of TAMRA
- Contains 3 PEG units
- Used in fluorescent dye applications
- Related to labeling chemistry
- A functional group type
- Belongs to rhodamine dyes
eMolecules 1217601-12-1 | PEG8-Ms | Broadpharm404.470 | C15H32O10S | 98.000 | CS(=O)(=O)OCCOCCOCCOCCOCCOCCOCCO | 1g | 433947000
PEG8-Ms | Broadpharm | 1217601-12-1404.470 | C15H32O10S | 98.000 | CS(=O)(=O)OCCOCCOCCOCCOCCOCCOCCO | 1g | 433947000
![Medchemexpress LLC Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]- | 1309460-27-2 | MFCD18916985 | 99.1% | 397.42 g/mol | C19H27NO8 | 1 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202266.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[[13-(4-formylphenyl)-13-oxo-3,6,9-trioxa-12-azatridec-1-yl]oxy]- | 1309460-27-2 | MFCD18916985 | 99.1% | 397.42 g/mol | C19H27NO8 | 1 G
A noncleavable polyethylene glycol (PEG) linker intended for antibody-drug conjugate research. It provides a 4-unit PEG spacer with an aldehyde-phenyl amido linkage and a terminal carboxylic acid for bioconjugation; supplied as a viscous, off-white to light yellow liquid with high purity and specific storage requirements.
- Noncleavable linker for antibody-drug conjugate research.
- High purity: 99.1%.
- Molecular weight: 397.42 g/mol.
- Chemical formula: C19H27NO8.
- CAS number: 1309460-27-2.
- Appearance: viscous liquid, off-white to light yellow.
- Storage: store at 4°C under nitrogen; in solution, -20°C (short term) or -80°C (long term).
- Packaged quantity: 1 G.
Cayman Chemical DBCO-NHS ester 50mg
An azido-reactive click-chemistry reagent; has been conjugated to various anticancer agents for targeting azido-labeled cancer cells in mice
![eMolecules 2107273-10-7 | N-(m-PEG9)-N'-(propargyl-PEG9)-Cy5 | Broadpharm1235.990 | C65H103ClN2O18 | 97.000 | [Cl-].COCCOCCOCCOCCOCCOCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 1mg | 298819344](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465123.JPG-250.jpg)
eMolecules 2107273-10-7 | N-(m-PEG9)-N'-(propargyl-PEG9)-Cy5 | Broadpharm1235.990 | C65H103ClN2O18 | 97.000 | [Cl-].COCCOCCOCCOCCOCCOCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 1mg | 298819344
N-(m-PEG9)-N'-(propargyl-PEG9)-Cy5 | Broadpharm | 2107273-10-71235.990 | C65H103ClN2O18 | 97.000 | [Cl-].COCCOCCOCCOCCOCCOCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 1mg | 298819344
Broadpharm N-Mal-N-bis(PEG2-NHS ester) | 2182601-73-4 | MFCD29912828 | 50mg
N-Mal-N-bis(PEG2-NHS ester) | Purity: 98% | MW: 682.632 | 2182601-73-4 | MFCD29912828 | 50mg